Sciex Breakfast Workshop: SWATH™ for Beginners

Date: Friday 3 February 2017
Time: 7.15am - 8.45am
Location: Heritage Ballroom, Mantra Lorne 
Breakfast: from 7.00am

• Dr. James Broadbent (Field Applications Specialist, SCIEX ANZ)
• Katie Glenn (Field Applications Specialist, SCIEX ANZ)
• Madeleine Otway (PhD Candidate, Children’s Medical Research Institute)

Since its release in 2012, SWATH™ has moved beyond being just a novel acquisition technique to being an indispensable tool in systems biology research, demonstrating particular advantages for the analysis of medium-to-large sample cohorts, and for laboratories focused on the in-depth proteomics study of a small number of organisms or systems. In this workshop, SCIEX ANZ Field Applications Specialists Dr. James Broadbent and Katie Glenn, along with Madeline Otway (PhD Candidate, Children’s Medical Research Institute), will recap the basics of SWATH™, with tips and tricks on all aspects of the journey from samples to knowledge, including; study design, ensuring reproducible sample preparation, best-practice liquid chromatography/mass spectrometry method settings for SWATH™ Acquisition & open-source and commercial software options for processing of SWATH™ data.

Thermo Fisher Scientific Breakfast Workshop: Proteome Discoverer 2.1: New features and outlook AND Practical guidelines for robust, accurate and meaningful quantitative proteomics

Date: Friday 3 February 2017
Time: 7.15am - 8.45am
Location: Heritage 2, Mantra Lorne 
Breakfast: from 7.00am

• Dr Bernard Delanghe (Product and Marketing Manager of Omics software Thermo Fisher Scientific)
• Dr Xiaoyue Jiang (Senior Strategic Marketing Specialist Thermo Fisher Scientific)

• Changing medicine: Proteome centric precision health - Jennifer Van Eyk
• Digestion-free targeted LC-MS quantification of circulating Thymosin beta 4 in heart failure - Chester Drum
• Quantitative proteomics reveals novel diagnostic markers of Parkinson’s disease - Giuseppe Infusini
• An immunoproteomics approach for the identification of novel influenza B T cell epitopes. - Patricia Illing

• What Proteomics can tell us about Platelets! - Albert Sickman
• A combination of omics strategies to elucidate the proteolytic networks in macrophage differentiation - Nestor Solis
• Lysine acetylation throughout axenic culture in the early-branching eukaryotic parasite, Giardia duodenalis - Samantha J Emery
• Signalling networks in the regulation of red blood cell integrity and survival. - Evan Ingley

• A proteogenomic approach to understanding adaptive immunity in bats - Amanda P Woon
• A proteomic investigation of diseases of Sydney rock oysters: A step towards breeding better oysters - Vineet Vaibhav
• Characterisation of the Campylobacter jejuni Cj0025c nutrient transporter using a multi-omics approach - Lok Man
• Biomarker Signatures in Melanoma - Erin Sykes
• Quantitative proteomic analysis of the exercise-induced extracellular vesicle proteome - Martin Whitham
• The protein landscape of the inner ear of a native fish - Oliver R B Thomas

• Development of a novel encyclopaedic peptide spectral library using the liquid fraction of sheep blood - Saul Chemonges
• Sample Replication Effects on Statistical Power in Multiplexed Immunoassay Analysis - Edmond Breen
• Cavitron ultrasonic surgical aspirates are novel sources of glioblastoma-derived extracellular vesicles - Susannah Hallal
• Digestion-free Targeted LC-MS Quantification of Circulating Thymosin beta 4 in Heart Failure - Chester Drum
• Generation of PCT SWATH-MS based proteomic profile of rat organs - Sadia Mahboob
• Physical activity elevates circulating levels of the neuroprotective LG3 peptide: potential novel stroke therapy? - Tony J Parker
• The future of glycan MALDI mass spectrometry imaging - Matthew T. Briggs
• Glioma Stem Cells Induce Invasion-like Structures in Normal Astrocytes via Extracellular Vesicles - Susannah Hallal
• High throughput and accurate quantitation of phosphoproteomics for biological signaling - Xiaoyue Jiang
• Characterising dynamic changes to MLKL during necroptotic cell death. - Jarrod J Sandow
• A DIA-based Phosphoproteomic Study of Signalling Transduction via the Chemokine Receptor CCR2 - Cheng Huang
• Investigation of SOCS5 signalling complexes by mass spectrometry uncovers a role in breast cancer - Edmond M Linossi
• PTMOracle: a Cytoscape app for co-visualising and co-analysing post-translational modifications in protein interaction networks - Aidan P Tay
• Exploring the phosphoproteome to understand the roles of p38 and IAPs in TNF signalling  - Denise A. Heckmann
• Proteomic and degradomic analysis of a virulence-associated serine peptidase from Campylobacter jejuni - Joel A Cain
• The mystery of tungsten: An unexpected bond with Cu,Zn-SOD - Larissa Lago
• Quantitative characterisation of the paediatric burn blister fluid proteome using SWATH MS to assist clinical diagnosis - Tuo Zang
• The N-terminome of Mycoplasma hyopneumoniae reveals novel insights into protein processing - Iain J Berry
• A comprehensive proteomic study of cancer cell derived microparticles - Penelope V Dalla
• Temporal profiling of protein phosphorylation during myocardial reperfusion injury - Desmond K Li
• In‑depth mass spectrometry characterisation of S. cerevisiae protein methyltransferases: are they endpoints of signalling pathways? - Daniel Winter
• METTL21B is a novel human lysine methyltransferase of translation elongation factor 1A: discovery by CRISPR/Cas9 knock out - Joshua Hamey
• Development and validation of a pipeline for the biophysical characterization therapeutic monoclonal antibodies using MALDI-HXMS - Thomas Nebl

Sciex Afternoon Workshop:

Towards Precision Medicine; the SCIEX Clinical Proteomics Workshop

Date: Friday 3 February 2017
Time: 2.45pm - 4.45pm
Location: Heritage Ballroom, Mantra Lorne

• Professor Jennifer Van Eyk (Cedars-Sinai Medical Center, USA)
• Dr. Christie Hunter (Director of Global Technical Marketing, SCIEX USA)
• Dr. James Broadbent (Field Applications Specialist, SCIEX ANZ)

What if we could deliver the right treatment at the right time, to the right person to better, more effectively treat complex disease? This is the promise of precision medicine, to be able to approach complex disease treatment and prevention by taking into account individual variability in genes, environment, and lifestyle for each person. Many of today’s medical treatments have been designed for the masses while the promise of precision medicine is to build treatments that are constructed around specific disease and individual characteristics. As the promise of precision medicine continues to evolve, researchers will need powerful tools to perform the Omics research that creates the scientific foundation of precision medicine. SCIEX industrialized proteomics solutions, using SWATH® Acquisition-based workflows and powered by the cloud with the OneOmics™ Project, will enable large-scale proteome studies on a scale unachievable by other methods. 

The SCIEX Clinical Proteomics workshop features a special presentation from Professor Jennifer Van Eyk (Cedars-Sinai Medical Center, CA, USA), entitled “Industrialization: creating proteomic scalability to impact science” and updates from Dr. Christie Hunter (Director of Global Technical Marketing, SCIEX USA) and Dr. James Broadbent (Field Application Specialist, SCIEX ANZ) on the latest developments in SCIEX mass spectrometry and related technologies that bring us closer to the era of precision medicine.

Thermo Fisher Scientific Afternoon Workshop

Building ProteomeTools based on a complete synthetic human proteome

Date: Friday 3 February 2017
Time: 2.45pm - 4.45pm
Location: Heritage 2, Mantra Lorne

Join us at our Lorne Proteomics Friday afternoon workshop with food and drinks provided to hear Prof Bernhard Kuster, the chair of proteomics and bioanalytics, Technische Universität München (TUM) School of Life Sciences Weihenstephan speak on his latest major project.

The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. In this presentation, the generation and multimodal LC-MS/MS analysis of >330,000 synthetic tryptic peptides representing essentially all canonical human gene products will be described and examples for the use of this data will be presented. The resource will be extended to more than one million peptides within two years and all data will be made available to the public in ProteomicsDB and proteomeXchange.

• Glycoproteomics for analysis of the regulation and evolution of protein glycosylation - Ben Schulz
• Developing a glycoproteomics tool kit using synthetic N-glycopeptides - Daniel Kolarich
• Revealing glycan structural epitopes using a simplified LC-MS/MS data acquisition and analysis platform for glycomics - Christopher Ashwood
• Evaluating the relationship between N-Glycosylation and protein stability in Campylobacter jejuni - Joel A Cain

APS Conference Dinner

Date: Friday 3 February 2017
Time: 7.30pm - 10.30pm
Location: Lorne Surf Life Saving Club
Cost: (Ticketed Event)

The APS Conference Dinner is without a doubt the social highlight of the conference. This is an event not to miss.